September 11, 2025HeartOpen Access

Prehospital 12-lead ECG and outcomes in acute coronary syndrome

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Discussion

Population-based cohort study reveals improved mortality and reperfusion outcomes after using 12-lead ECG in patients with acute coronary syndrome.

Patients receiving a prehospital ECG showed lower 30-day mortality at 7.1%, compared to 10.9% for those who did not.
The use of prehospital ECG increased from 74.2% in 2010 to 85.0% in 2017, indicating a growing adoption in EMS protocols.
Reperfusion was more common in patients with ST-elevation myocardial infarction, at 84.5% for those receiving prehospital ECG.
Adjusted odds ratios indicated a significant reduction in mortality with prehospital ECG, showing an OR of 0.77 at 30 days.

Driscoll et al. (2025) studied this question.

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Population-based cohort study reveals improved mortality and reperfusion outcomes after using 12-lead ECG in patients with acute coronary syndrome.