September 11, 2025PLoS ONEOpen Access

Safety and contribution of elderly whole blood donors after raising the upper age limit: Hemovigilance data from a Chinese region from 2012 to 2023

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Analysis of hemovigilance data reveals improved outcomes for elderly blood donors, suggesting enhanced donor health and lower deferral rates.

Elderly blood donors aged 56–60 increased their contributions tenfold over 12 years, enhancing the blood supply.
Lower deferral rates were found among older male donors compared to younger males, whereas older females showed higher deferral rates.
Vasovagal reactions and rates of HBV, HCV, and syphilis infections were lower among elderly donors than younger ones.
The positive HIV reaction rate was higher in older female donors than in their younger counterparts.

Yang et al. (2025) studied this question.

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Analysis of hemovigilance data reveals improved outcomes for elderly blood donors, suggesting enhanced donor health and lower deferral rates.