Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 11, 2025Biotechnology and Applied Biochemistry

Comprehensive Analysis of Gene Expression and Biomarkers in Sepsis Using Bioinformatics, Network Pharmacology and Molecular Modeling Approaches

View Full Paper
Ask AI
Bookmark
Share

Authors

ZTZhengyun TianWWWeiwei WangHHHao Hao

Discussion

Loading...

Member takes

Overview

Bioinformatics reveals biomarkers in sepsis and COVID-19, highlighting TCM compounds as potential therapies.

Key Points

  • Key DEGs associated with sepsis were identified, and promising therapeutic targets like RRM2 were revealed.
  • Molecular docking showed strong binding affinity of TCM compounds, including Salvianolic Acid C, to target proteins.
  • Bioinformatics analysis utilized gene expression data and advanced methodologies for functional enrichment.
  • The integrated approach supports the identification of novel drug candidates needing experimental validation.

Cite This Study

Tian et al. (2025) studied this question.

synapsesocial.com/papers/68d41405713b0b5dfea623bahttps://doi.org/10.1002/bab.70049
View Full Paper
Ask AI
Bookmark
Share