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September 11, 2025Infection Control and Hospital Epidemiology

Interrupted time-series analysis to evaluate the impact of a national antimicrobial stewardship campaign on antibiotic use among primary healthcare institutions: evidence from Central China

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Authors

YXYangting XuYWYingying WangHQHaiyong Qian

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Overview

Interrupted time-series analysis reveals significant declines in antibiotic consumption and broad-spectrum use in primary healthcare institutions.

Key Points

  • Antibiotic consumption in primary healthcare institutions declined by 35.96% after intervention, indicating effective policy implementation.
  • Post-intervention analysis showed a 41.97% reduction in broad-spectrum antibiotic use, emphasizing a shift towards responsible prescribing.
  • Data collected from 1510 primary healthcare institutions across various regions showed notable disparities in policy impact.
  • The national action plan to combat antimicrobial resistance indicates regional variations in antibiotic stewardship outcomes.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68d413ff713b0b5dfea6216ehttps://doi.org/10.1017/ice.2025.10266
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