September 10, 2025BJS OpenOpen Access

Prognosis of lymph node metastasis confined to lateral pelvic or mesenteric nodes in mid–low rectal cancer: multicentre retrospective cohort study

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Discussion

Retrospective analysis reveals distinct survival outcomes based on lateral pelvic and mesenteric lymph node involvement in cancer patients.

Metastasis confined to lateral pelvic lymph nodes shows significantly better prognosis than dual involvement.
Overall survival for lateral pelvic node metastasis is 78.6%, compared to 47.2% for both lymph node types.
The study analyzed clinicopathological features of 407 patients with mid-low rectal cancer post-surgery.
Findings suggest comparable prognosis and pathological features for lateral pelvic and mesenteric node metastases.

Huang et al. (2025) studied this question.

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Retrospective analysis reveals distinct survival outcomes based on lateral pelvic and mesenteric lymph node involvement in cancer patients.