September 10, 2025Annals of HematologyOpen Access

Is splenectomy one of the contributory factors to pulmonary hypertension? An analysis of splenectomized hemolytic anemia and immune thrombocytopenia patients

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Authors

ZBZeliha BirsinIstanbul University-Cerrahpaşa ASAyşe Salihoğlu KTKardelen Ohtaroğlu Tokdil

Discussion

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Implication

Prospective analysis finds splenectomy does not significantly affect pulmonary hypertension risk in patients with immune thrombocytopenia and hemolytic anemia, suggesting underlying conditions are key.

Key Points

Splenectomy does not significantly contribute to pulmonary hypertension risk according to the findings.
Only 1 patient with immune thrombocytopenia and 3 with hemolytic anemia were diagnosed with pulmonary hypertension.
Echocardiography revealed low pulmonary hypertension risk in splenectomized hemolytic anemia patients with decreased hemolysis post-splenectomy.
The study indicates that pulmonary hypertension development is more related to the underlying disease rather than splenectomy itself.

Cite This Study

Birsin et al. (2025) studied this question.

synapsesocial.com/papers/68d413ee713b0b5dfea618a4 https://doi.org/10.1007/s00277-025-06583-9

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