Systematic analysis reveals six druggable genes linked to ischemic stroke, highlighting their potential implications.
Key Points
Identified six potential druggable genes significantly associated with ischemic stroke risk, offering new therapeutic targets.
Mendelian randomization analysis confirmed causal relationships between druggable genes and ischemic stroke, enhancing understanding of genetic contributions.
Colocalization analysis indicated six genes had significant associations with ischemic stroke, showing relevance across blood and brain tissues.
Phenome-wide MR analysis suggested that some identified genes have correlations with other conditions, indicating broader implications beyond ischemic stroke.