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September 10, 2025Russian Journal of Pediatric Hematology and OncologyOpen Access

Treatment of children with relapsed and refractory classical Hodgkin’s lymphoma: the experience of two centers

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Authors

NTNatalia S. TsaplinaАКА. В. КозловТВТ. Т. Валиев

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Overview

Analysis reports significant survival rates in children treated for relapsed and refractory lymphoma, suggesting brentuximab vedotin enhances outcomes.

Key Points

  • The 10-year overall survival rate was 76%, indicating effective treatment strategies for relapsed and refractory classical Hodgkin lymphoma.
  • Inclusion of brentuximab vedotin resulted in a higher relapse-free survival rate of 83%, emphasizing its potential role in therapy.
  • Seventy-three patients aged 5.5 to 18.6 years were included in this study, providing insights into treatment effectiveness across a pediatric population.
  • This cooperative effort between two Russian clinics demonstrates the importance of targeted therapies and stem cell transplantation in improving patient outcomes.

Cite This Study

Tsaplina et al. (2024) studied this question.

synapsesocial.com/papers/68c2443bb210217d647aa39dhttps://doi.org/10.21682/2311-1267-2024-11-3-22-29
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