Network meta-analysis shows third-generation vertebral augmentation is superior to non-surgical management, indicating improved pain and functional outcomes.
Key Points
Third-generation percutaneous vertebral augmentation provides better pain relief than non-surgical management in osteoporotic vertebral compression fractures.
On average, pain intensity decreased more significantly with TVA and PKP compared to non-surgical management at both short-term and long-term follow-ups.
This network meta-analysis involved 46 studies that compared various interventions for osteoporotic vertebral compression fractures and measured multiple outcomes.
The findings suggest that while PKP preserves vertebral body height, TVA generally improves pain, disability, and quality of life more effectively than other methods.