This analysis explores antimicrobial efficacy and in silico interactions of plant extracts in germicidal applications, suggesting safe alternatives.
Key Points
Rosemary and hibiscus extracts exhibit significant antimicrobial activity, confirming their potential as safer germicidal ingredients.
In silico analysis revealed bioactive compounds with strong negative binding energies against bacterial proteins involved in resistance.
The compound Tricyclo[20.8.0.0(7,16)]triacontane,1(22),7(16)-diepoxy showed a docking score of -11 kcal/mol against S.aureus, indicating strong antibacterial potential.
Hibiscus extract's 1,3-Diphenyl-1,2-butanediol achieved a docking score of -7.5 kcal/mol against K. pneumoniae, showcasing its promising bioactivity.