Strain Improvement Through Genetic Engineering and Synthetic Biology for the Creation of Microalgae with Enhanced Lipid Accumulation, Stress Tolerance, and Production of High-value
This review demonstrates improvements in lipid accumulation and stress tolerance in microalgae, highlighting genetic engineering and synthetic biology strategies.
Key Points
Enhanced lipid accumulation was achieved, improving the potential for biofuel production from microalgae.
CRISPR/Cas9 genome editing proved effective for modifying genetic pathways, enabling more efficient lipid synthesis.
Recent advances in synthetic biology offer new strategies for optimizing stress tolerance and metabolic versatility of microalgal strains.
Challenges in achieving scalable production and stability of engineered microalgae remain, indicating the need for further research.