Increased Antimicrobial Consumption, Isolation Rate, and Resistance Profiles of Multi-Drug Resistant Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii During the COVID-19 Pandemic in a Tertiary Healthcare Institution
Observational analysis reveals increased antibiotic consumption and resistance profiles in Klebsiella pneumoniae and Pseudomonas aeruginosa during the COVID-19 pandemic.
Key Points
Increased antibiotic resistance profiles for KPN and PAE were noted during the pandemic, significantly impacting healthcare.
Total antibiotic consumption surged by 72%, with substantial rises in key antibiotics such as vancomycin and meropenem.
MDR strains of KPN and PAE correlated positively with mechanical ventilation usage among patients, evidencing heightened risk.
Statistical analysis showed significant changes in resistant bacterial strains during the pandemic period across all hospital departments.