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September 10, 2025European Journal of NeuroscienceOpen Access

Cannabidiol and Alzheimer Disease: A Comprehensive Review and In Silico Insights Into Molecular Interactions

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Authors

JMJoão Vitor Mello-HortegaCOCarolina Souza-de OliveiraVAVitória Emily Santana De Araújo

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Overview

Comprehensive review explores cannabidiol's effects on amyloid pathways and neuroinflammation in AD.

Key Points

  • Cannabidiol shows potential therapeutic effects on alzheimer disease, impacting key pathological features.
  • The review synthesizes evidence on cannabidiol's influence on amyloid plaques and tau phosphorylation.
  • Observational analysis of gene expression indicates cannabidiol modifies biological pathways in alzheimer disease.
  • Results highlight the necessity for further research on cannabidiol's gene targets in alzheimer disease treatment.

Cite This Study

Mello-Hortega et al. (2025) studied this question.

synapsesocial.com/papers/68c24364b210217d647a6747https://doi.org/10.1111/ejn.70229
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