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September 10, 2025Drug Design Development and TherapyOpen Access

Molecular Pharmacological Interventions for Endometrial Cancer: A Comprehensive Review

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Authors

WQWei QinYQYan QiQLQianwen Li

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Overview

This review explores pharmacological interventions targeting apoptosis and estrogen receptor pathways in endometrial cancer, suggesting potential personalized therapy options.

Key Points

  • Molecular pathways influencing apoptosis and estrogen signaling are crucial in endometrial cancer development.
  • Pharmacological strategies like BH3 mimetics show promise in targeting Bcl-2 family pathways to combat resistance.
  • Natural compounds such as curcumin and Ganoderma lucidum polysaccharides exhibit efficacy in preclinical studies for endometrial cancer.
  • The ongoing challenge of resistance and adverse effects highlights the need for personalized therapeutic strategies in treatment.

Cite This Study

Qin et al. (2025) studied this question.

synapsesocial.com/papers/68c24317b210217d647a5e21https://doi.org/10.2147/dddt.s524181
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