The Role of Gut Microbiota in the Modulation of Pulmonary Immune Response to Viral Infection Through the Gut-Lung Axis

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Disruption of gut microbiota can impair pulmonary immune response, increasing viral infection susceptibility.
Probiotic use has shown promise in reducing respiratory failure risk in COVID-19 patients, enhancing overall immune response.
Interventions like fecal microbiota transplantation significantly improve resistance to influenza in animal models.
Future research should focus on personalized microbiome therapies to enhance treatment efficacy against respiratory infections.

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Review uncovers how gut-lung axis modulates immune response to viral infections, suggesting probiotics and FMT may enhance outcomes.

Chen et al. (2025) studied this question.

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