Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Scientific ReportsOpen Access

Identification of SNCA and DRD2 as key genes linking parkinson’s disease and circadian rhythm through bioinformatics analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

JZJie ZhangGZGuoli ZhangWLWei Liu

Discussion

Loading...

Member takes

Overview

Bioinformatics analysis reveals SNCA and DRD2 as hub genes for Parkinson's Disease and circadian rhythm, suggesting new therapeutic targets.

Key Points

  • SNCA and DRD2 were identified as key genes linking Parkinson's disease and circadian rhythm.
  • A total of 659 PD-related DEGs and 2555 CR-related genes were screened using bioinformatics methods.
  • The constructed mRNA-miRNA regulatory network showed substantial associations with multiple miRNAs.
  • Molecular docking verified that specific traditional Chinese medicine components have strong binding energies with target proteins.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68c24317b210217d647a5ae5https://doi.org/10.1038/s41598-025-16854-0
View Full Paper
Ask AI
Bookmark
Share