September 10, 2025BMC Public HealthOpen Access

Effects of air pollutants on the incidence, progression, and mortality of idiopathic pulmonary fibrosis: a systematic review and meta-analysis

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Discussion

Systematic review shows air pollutants increase IPF incidence and progression, highlighting health risks.

Increased risk of idiopathic pulmonary fibrosis progression is associated with higher levels of PM2.5.
Meta-analysis indicates a 32% increased risk for idiopathic pulmonary fibrosis progression for every 10 µg/m3 increase in NO2.
Systematic evaluation used data from 18 studies involving 858,557 participants to assess air pollutants' effects on IPF.
Findings suggest that reducing pollutants like NO2 and PM2.5 could significantly lower the risk of developing or worsening IPF.

Luo et al. (2025) studied this question.

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