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September 10, 2025Pain Management

Late response to anti-CGRP therapy for migraine

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Authors

OMOreste MarsicoMLMarta LioiMTMichele Trimboli

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Overview

Narrative review shows late responders to anti-CGRP therapy in migraine patients, suggesting longer treatment duration may be beneficial.

Key Points

  • Around one-third of patients initially non-responsive to anti-CGRP therapies showed improvement by 6 months.
  • Real-world studies indicate that some migraine patients are late responders, achieving significant benefits beyond the initial 3-month period.
  • The review highlights the importance of understanding mechanisms behind late responses to CGRP therapy to optimize treatment duration.
  • Investigating patient responses over a longer timeframe could lead to improved migraine management strategies.

Cite This Study

Marsico et al. (2025) studied this question.

synapsesocial.com/papers/68c242e0b210217d647a4e7fhttps://doi.org/10.1080/17581869.2025.2550931
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