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September 10, 2025Strahlentherapie und OnkologieOpen Access

Head and neck squamous cell carcinoma in adults aged 45 or younger—an analysis of two tertiary cancer centres

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Authors

CSCharlotte SchmitterSSSören SchnellhardtSSSabine Semrau

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Overview

Retrospective analysis of survival and recurrence in patients aged 45 or younger with HNSCC, indicating potential for improved treatment strategies.

Key Points

  • Overall survival was 79.7% at 2 years for patients with head and neck squamous cell carcinoma.
  • Disease-free survival rate was 73.4% at 2 years, while 14.6% had locoregional recurrences.
  • Univariate analysis revealed significant factors impacting disease-free survival, including alcohol consumption and UICC stage.
  • Locoregional recurrences were the most common, highlighting a need for potential intensified treatment approaches.

Cite This Study

Schmitter et al. (2025) studied this question.

synapsesocial.com/papers/68c242e0b210217d647a4c10https://doi.org/10.1007/s00066-025-02448-2
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