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September 10, 2025

Therapeutic strategies for graft-versus-host disease in the new era.

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Authors

MTMasako Toyosaki

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Overview

Overview of therapeutic strategies and biomarkers for acute and chronic gvhd, highlighting recent developments.

Key Points

  • Graft-versus-host disease remains a major cause of mortality post-transplantation, with 40-60% of patients suffering from acute gvhd.
  • Recent advancements in biomarkers and risk stratification strategies have enabled better management of acute gvhd and chronic gvhd.
  • A new severity classification system for acute gvhd could improve preemptive treatment strategies for patients undergoing transplants.
  • Three new drugs have been approved for the treatment of chronic gvhd, marking significant progress in therapeutic options.

Cite This Study

Masako Toyosaki (2025) studied this question.

synapsesocial.com/papers/68c24236b210217d647a25d9https://doi.org/10.11406/rinketsu.66.635
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