September 10, 2025Recent Advances in Drug Delivery and Formulation

Advancements in Enteric-coated Microspheres Formulation Development and Mangiferin Drug Delivery for the Treatment of Ulcerative Colitis

View Full Paper

Ask AI

Bookmark

Authors

SYSwati YadavCentral Institute of Freshwater Aquaculture RHRanjit Kumar HarwanshGLA University RMRupa MazumderJaypee Institute of Information Technology

Discussion

Member takes

Implication

Observational analysis showed reduced inflammation and oxidative stress in ulcerative colitis, suggesting mangiferin-loaded microspheres provide therapeutic benefits.

Key Points

Microspheres loaded with mangiferin significantly reduced the severity of ulcerative colitis.
Weight loss, ulcer activity scores, and oxidative stress markers improved with the treatment.
Colon samples indicated enhanced catalase and glutathione activity following mangiferin treatment.
The formulation's delayed-release properties may enhance treatment outcomes for ulcerative colitis.

Cite This Study

Yadav et al. (2025) studied this question.

synapsesocial.com/papers/68c241efb210217d647a173c https://doi.org/10.2174/0126673878362674250630062020

View Full Paper

Ask AI

Bookmark

Implication

Observational analysis showed reduced inflammation and oxidative stress in ulcerative colitis, suggesting mangiferin-loaded microspheres provide therapeutic benefits.