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September 10, 2025Indian Journal of Neonatal Medicine and ResearchOpen Access

Impact of Probiotics Supplementation on Enteral Feed Tolerance in Very Low Birth Weight Neonates: An Open Label Randomised Controlled Trial

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Authors

NVNarain Das VaswaniHVHunny VermaPDPoonam Dalal

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Overview

Randomised controlled trial shows probiotics enhance feed tolerance and reduce complications in VLBW neonates.

Key Points

  • Probiotics supplementation significantly reduced time to achieve full feeds in neonates.
  • Participants in the probiotic group took an average of 4.22 days to achieve full feeds versus 9.56 days in the control group (p<0.001).
  • An open-label randomised controlled trial was conducted at a tertiary care center involving 100 VLBW neonates.
  • Probiotics may reduce the incidence of complications like necrotising enterocolitis and sepsis in vulnerable populations.

Cite This Study

Vaswani et al. (2025) studied this question.

synapsesocial.com/papers/68c241efb210217d647a1275https://doi.org/10.7860/ijnmr/2025/75136.2446
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