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September 10, 2025Annals of Medicine and SurgeryOpen Access

Non-adherence to anti diabetic medication and associated factors in Nepal: a systematic review and meta-analysis

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Authors

APAsim PandeyPKPrajwal KhanalSPSamriddhi Parajuli

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Overview

Systematic review highlights a 56.3% non-adherence rate in diabetic patients, indicating illiteracy and poverty as key factors.

Key Points

  • The overall pooled prevalence of non-adherence to anti-diabetic medications is 56.3%, raising serious concerns for diabetes management.
  • Subgroup analysis revealed that non-adherence rates were 60.2% in rural areas, compared to 53.7% in urban settings, signaling a geographical disparity.
  • The relative risk of non-adherence among illiterate individuals is 1.373, emphasizing the significant impact of education on medication adherence.
  • Key factors against adherence include illiteracy, poverty, lack of health facilities, forgetfulness, medication costs, and the number of medications.

Cite This Study

Pandey et al. (2025) studied this question.

synapsesocial.com/papers/68c241efb210217d647a0f5ahttps://doi.org/10.1097/ms9.0000000000003563
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