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September 10, 2025Journal of Separation Science

Development and Validation of a Headspace Gas Chromatography–Mass Spectrometry Method for the Identification and Quantification of Glycol Ethers in Cosmetic Cream Formulations

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Authors

IMImane MECHERIUniversity Frères Mentouri Constantine 1RDRachid DjaferBadji Mokhtar-Annaba UniversityMDMohamed Dammak

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Implication

Analytical method detects glycol ethers in cosmetic formulations, indicating effective quantification and validation.

Key Points

  • The method successfully quantifies glycol ethers in cosmetic creams, achieving recoveries between 96.72% and 100.40%.
  • Detection limits for glycol ethers ranged, with ethylene glycol dimethyl ether having a limit of 1.39 µg/mL.
  • Samples undergo extraction with ethanol and vortexing, followed by analysis via headspace gas chromatography mass spectrometry.
  • Validation included parameters like linearity and accuracy, confirming the method's reliability for detecting glycol ethers.

Cite This Study

Mecheri et al. (2025) studied this question.

synapsesocial.com/papers/68c241acb210217d647a0002https://doi.org/10.1002/jssc.70243
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