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September 10, 2025Journal of NeuroimmunologyOpen Access

Harnessing the innate immune system for glioblastoma therapeutics

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Authors

HMHeather McLeanMDMatthew DrillAlfred HealthRSRichard P. SequeiraAlfred Health

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Implication

Review discusses innate immune mechanisms in glioblastoma, suggesting potential strategies to improve treatment outcomes.

Key Points

  • Harnessing innate immunity may enhance treatment efficacy against glioblastoma, improving patient outcomes.
  • The review highlights the role of immune cells such as microglia and macrophages in promoting treatment resistance.
  • Insights into the immunosuppressive tumour microenvironment provide a basis for developing novel therapeutic strategies.
  • Current preclinical and clinical trials are focused on leveraging innate immune cells to combat glioblastoma effectively.

Cite This Study

McLean et al. (2025) studied this question.

synapsesocial.com/papers/68c2416eb210217d6479fadchttps://doi.org/10.1016/j.jneuroim.2025.578713
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