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September 10, 2025Nepal Journal of BiotechnologyOpen Access

Potential Antimalarial Compounds from Spectroscopically Identified Compounds of Aqueous Stem-bark Extract of Magnifera indica: An In silico Approach

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Authors

ALAbdulhafiz LamiyaSMS. B. MuhammadAAA. J. Alhassan

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Overview

Spectroscopic techniques identify potential inhibitors of Plasmodium falciparum, suggesting new drug candidates.

Key Points

  • Oleic acid shows strong potential against plasmepsin II with a binding energy of -5.8 Kcal/mol.
  • Molecular docking analysis identified multiple phytochemicals as potential inhibitors for Plasmodium falciparum targets.
  • ADMET analysis indicates favorable pharmacokinetics and toxicity for most identified compounds.
  • Phthalic acid dibutyl ester presents slight nephrotoxicity, signaling the need for further validation before clinical use.

Cite This Study

Lamiya et al. (2025) studied this question.

synapsesocial.com/papers/68c2416eb210217d6479f81dhttps://doi.org/10.54796/njb.v13i1.383
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