Castleman Disease: Insights from a Case Series and Literature Review

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Case series presents diagnostic challenges and treatment variations in castleman disease, highlighting a need for refined management strategies.

Castleman disease presents with diverse clinical presentations, complicating diagnosis and treatment.
Histopathology plays a critical role in distinguishing castleman disease from malignancies or autoimmune disorders.
Treatment for unicentric disease typically involves surgery, while multicentric disease may require immunomodulators.
Emerging therapies like cytokine-targeted approaches show potential in managing refractory cases of castleman disease.

James et al. (2025) studied this question.

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Case series presents diagnostic challenges and treatment variations in castleman disease, highlighting a need for refined management strategies.