Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025International Journal of Research in Pharmacology & Pharmacotherapeutics

Notch Signalling in Liver Disease: A Comprehensive Analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

KBKeerthi BirudarajuDRDasari RajeshCAChennaboina Soumya Chennuri Akshitha

Discussion

Loading...

Member takes

Overview

Comprehensive analysis reveals Notch signaling's influence on liver diseases, suggesting novel therapeutic avenues. Highlights include cholangiopathies and hepatocellular carcinoma.

Key Points

  • Aberrant notch signaling contributes to the progression of various liver diseases, including NAFLD and HCC.
  • Notch modulation has the potential to improve disease management in hepatic disorders.
  • Therapies targeting notch, like γ-secretase inhibitors, show promise but face challenges like toxicity.
  • This analysis underscores the need for context-specific interventions to enhance patient outcomes in liver disease.

Cite This Study

Birudaraju et al. (2025) studied this question.

synapsesocial.com/papers/68c2416eb210217d6479ea1ehttps://doi.org/10.61096/ijrpp.v14.iss1.2025.16-24
View Full Paper
Ask AI
Bookmark
Share