Case-control study assesses the role of IP-10 gene polymorphisms on HBsAg loss in chronic HBV patients, suggesting limited predictive value.
Key Points
No significant association was found between IP-10 gene polymorphisms and HBsAg loss in patients with chronic hepatitis B.
Detection of three polymorphisms within the IP-10 gene revealed no significant differences in genotype or allele distributions between the case and control groups.
The analysis included 60 patients who achieved HBsAg loss and 60 HBsAg positive controls, collected from a larger cohort over 17 years.
Findings imply that specific polymorphisms in the IP-10 gene cannot serve as reliable predictive markers for HBsAg loss.