Observational analysis found extracts from Fomitopsis pinicola reduced viability of Borrelia burgdorferi, indicating potential as a natural antimicrobial agent.
Key Points
Fomitopsis pinicola extracts significantly reduced the viability of Borrelia burgdorferi cells and biofilm mass.
The L2 extract produced a notable inhibition zone of 15.33 ± 0.47 mm against Klebsiella pneumoniae.
Extracts showed dose-dependent antioxidant activity with IC50 ranging from 1.9 to 6.7 mg/mL.
Cytotoxicity tests indicated minimal effects on normal cells, supporting safety for potential human use.