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September 10, 2025Pakistan Journal of Health Sciences

Treatment-Related Mortality in Pediatric Acute-Lymphoblastic and Myeloid Leukemia: Experience from A Low- and Middle-Income Setting

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Authors

SGSana GullAAAlia AhmadLILuqman Iqbal

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Overview

Retrospective cohort study assessed treatment-related mortality in children with acute leukemia, indicating significant infection risk factors.

Key Points

  • Infection-related causes accounted for 93% of treatment-related mortality in children with acute leukemia.
  • The study observed that 136 (75%) cases were acute-lymphoblastic-leukemia while 45 (25%) were acute-myeloid-leukemia.
  • Major risk factors influencing mortality were under-nutrition, low platelet counts, and high CRP levels in patients undergoing chemotherapy.
  • The findings suggest that improving infection prevention and supportive care could substantially reduce treatment-related mortality.

Cite This Study

Gull et al. (2025) studied this question.

synapsesocial.com/papers/68c24126b210217d6479d65fhttps://doi.org/10.54393/pjhs.v6i7.3125
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