September 10, 2025Pakistan Journal of Health Sciences

Assessing the Effect of Hormonal Contraceptives on Oxidative Stress and Lipid Metabolism in Reproductive Age Women

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Authors

AMAnjum MahmoodKhyber Medical College RKRazeeya KhanUniversity of the Witwatersrand HAHumayun AnjumBaylor Scott & White Health

Discussion

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Implication

Comparative cross-sectional analysis reveals hormonal contraceptives elevate oxidative stress and worsen lipid profile in reproductive-age women, suggesting metabolic risks.

Key Points

Hormonal contraceptive users show significantly increased oxidative stress markers and reduced antioxidant levels, indicating metabolic changes.
Cholesterol, triglycerides, and LDL-C are significantly higher in contraceptive users, while HDL-C is notably lower, reflecting poor lipid profiles.
This comparative cross-sectional study analyzed blood samples from women aged 18-40, assessing oxidative stress and lipid profile.
Elevated oxidative stress and adverse lipid changes with contraceptive use highlight potential cardiovascular risks requiring monitoring.

Cite This Study

Mahmood et al. (2025) studied this question.

synapsesocial.com/papers/68c24126b210217d6479d65a https://doi.org/10.54393/pjhs.v6i7.3319

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Implication

Comparative cross-sectional analysis reveals hormonal contraceptives elevate oxidative stress and worsen lipid profile in reproductive-age women, suggesting metabolic risks.