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September 10, 2025International Journal of Experimental Pathology

Molecular epidemiology of Epstein–Barr virus in gastric cancer patients compared to healthy control group in Shiraz, Iran

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Authors

FHFatemeh HosseiniSFSahel FarajiMAM. Sib Ansari

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Overview

Cross-sectional study finds 1.88% EBV positivity in gastric cancer patients, highlighting possible mechanisms of infection.

Key Points

  • The study revealed a lower prevalence of EBV in gastric cancer tissue, with only 1.88% positivity compared to 22.62% in control samples.
  • Analysis showed that all EBV-positive gastric cancer patients were female, indicating potential gender-related factors in EBV infection.
  • Nested PCR methods were employed to investigate EBV presence in formalin-fixed paraffin-embedded tissue samples from both groups.
  • The findings suggest that EBV may have different roles in gastric cancer carcinogenesis compared to its prevalence in healthy individuals.

Cite This Study

Hosseini et al. (2025) studied this question.

synapsesocial.com/papers/68c24126b210217d6479d5cchttps://doi.org/10.1111/iep.70004
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