Impact of Molecular and Cytogenetic Responses on Long-Term Outcomes in Children and Adolescents With Chronic Myeloid Leukemia: A Retrospective Study From India
Retrospective study reveals that molecular and cytogenetic responses significantly enhance survival rates in children and adolescents with chronic myeloid leukemia.
Key Points
Achieving complete cytogenetic response at 12 months leads to a 100% five-year survival rate in pediatric CML patients.
Among patients surveyed, 91% were alive at long-term follow-up with a median duration of 62 months.
Those achieving early molecular response had a notable five-year survival rate of 97.4%, indicating the importance of early response monitoring.
The findings underline the need for improved response tracking and adherence to treatment protocols in low- and middle-income countries.