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September 10, 2025Scientific ReportsOpen Access

Immune profiling of canine B cell lymphoma reveals cross-species conservation of prognostic markers

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Authors

DDDillon DidehvarJLJennifer LenzBPBrandon Peng

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Overview

Observational analysis of immune profiles reveals biomarkers indicating remission duration in canine B cell lymphoma, suggesting insights into treatment responses.

Key Points

  • Increased T cell transcripts are linked to longer remissions in canine B cell lymphoma.
  • IL2RB expression correlates with favorable outcomes in dogs undergoing chemotherapy for lymphoma.
  • Higher angiogenic markers predict shorter remissions, impacting treatment success in canine patients.
  • Macrophage-associated cytokines are elevated in treatment naive samples, influencing immune dynamics in relapsed cases.

Cite This Study

Didehvar et al. (2025) studied this question.

synapsesocial.com/papers/68c240deb210217d6479d29bhttps://doi.org/10.1038/s41598-025-13389-2
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