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September 10, 2025Biocaster Jurnal Kajian Biologi

The Role of Interleukin 1β, Fibroblast Growth Factor, Fibroblasts, Keratinocytes, Granulation Tissue and Collagen Density in the Wound Healing Phase (Study of Wound Healing in the Inflammation, Proliferation, and Remodeling Phases)

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Authors

ACAntonius ChristantoRCRisya CilmiatyMSMade Setiamika

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Overview

This scoping review examines interleukin 1β and fibroblast growth factors in wound healing phases, highlighting their implications for regenerative therapies.

Key Points

  • Elevated IL-1β degrades collagen, impairing wound healing and suggesting a role in inflammation.
  • Fibroblast-derived exosomes carrying miR-93-5p delay diabetic wound healing, affecting cellular mechanisms.
  • Controlled delivery of growth factors boosts fibroblast proliferation and collagen deposition, enhancing tissue repair.
  • Natural compounds like red fruit oil improve angiogenesis and collagen synthesis, promoting better healing.

Cite This Study

Christanto et al. (2025) studied this question.

synapsesocial.com/papers/68c240deb210217d6479cf95https://doi.org/10.36312/biocaster.v5i3.399
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Also Consider

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  1. 1Biophysical approach to studying protein interactions in skin wound healing2025
  2. 2Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation2025
  3. 3Correction of regulatory molecules expression at the inflammation stage using photobiomodulation therapy in chronic wound modeling2025
  4. 4Wound Healing: Molecular Mechanisms, Antimicrobial Peptides, and Emerging Technologies in Regenerative Medicine2025 · 34 citations
  5. 5The Roles of Micronutrition and Nutraceuticals in Enhancing Wound Healing and Tissue Regeneration: A Systematic Review2025 · 22 citations