Rare Metastatic Pattern: Serous Ovarian Carcinoma Mimicking Primary Breast Cancer – Two Case Reports

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Discussion

Case reports detail the clinical characteristics and diagnostic methods in rare metastatic patterns, highlighting their implications.

Metastasis from high-grade serous ovarian carcinoma to the breast is exceptionally rare, accounting for only 0.07% of ovarian cancer cases.
One patient with early diagnosis and comprehensive treatment including neoadjuvant chemotherapy achieved normalization of CA-125 levels and showed no active lesions.
Immunohistochemical tissue analysis was crucial for accurately diagnosing breast metastasis from ovarian cancer in these cases.
Timely diagnosis and a multidisciplinary treatment approach significantly improve clinical outcomes in metastatic cases.

Aidarov et al. (2025) studied this question.

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