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September 10, 2025Frontiers in Bioengineering and BiotechnologyOpen Access

Regulation of RHBDD1 in the invasion of esophageal cancer cells via ELK3/Wnt/β-catenin signaling pathway

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Authors

BXBing XuHCHui ChenXSXinchen Sun

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Overview

In vitro and in vivo analysis reveals RHBDD1's role in promoting esophageal cancer cell invasion, suggesting potential therapeutic targets.

Key Points

  • RHBDD1 enhances cell invasion and migration in esophageal cancer cells, promoting aggressive behavior.
  • Knockdown of RHBDD1 reduced lung and liver metastasis in vivo, indicating its role in cancer spread.
  • The study employed in vitro cell culture and in vivo mouse models to investigate molecular mechanisms.
  • Findings highlight RHBDD1 as a critical factor in epithelial-mesenchymal transition and cancer progression.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68c240deb210217d6479c3bahttps://doi.org/10.3389/fbioe.2025.1604859
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