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September 10, 2025Frontiers in PharmacologyOpen Access

Assessing the adherence of large language models to clinical practice guidelines in Chinese medicine: a content analysis

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Authors

WZWeilong ZhaoHLHonghao LaiBPBei Pan

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Overview

Cross-sectional analysis reveals varying accuracy of LLMs in adhering to clinical practice guidelines in CM, suggesting potential for enhanced knowledge dissemination.

Key Points

  • DeepSeek-v3 and DeepSeek-r1 achieved superior performance in answering clinical questions in both English and Chinese.
  • All large language models demonstrated higher accuracy in Chinese than in English, indicating language proficiency influence.
  • Significant differences in accuracy were noted across question categories, particularly in medication based on differential diagnosis.
  • Moonshot-v1 provided the highest safety disclaimer rates, showcasing better risk communication in clinical settings.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/68c240deb210217d6479c0ffhttps://doi.org/10.3389/fphar.2025.1649041
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