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September 10, 2025CancersOpen Access

Advances and Challenges in the Management of Myelodysplastic Syndromes

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Authors

JSJessica M. StempelTKTariq KewanAZAmer M. Zeidan

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Overview

This review highlights progress in myelodysplastic syndromes treatment, focusing on new prognostic tools and therapeutic options.

Key Points

  • Significant advances have been made in understanding myelodysplastic syndromes and their progression to acute myeloid leukemia.
  • New agents like luspatercept and imetelstat are evolving treatment paradigms for lower-risk myelodysplastic syndromes.
  • Current management strategies emphasize individualized treatment based on integrated clinical, cytogenetic, and molecular evaluations.
  • Ongoing challenges include the standard use of hypomethylating agents and the need for effective combination therapies.

Cite This Study

Stempel et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479b58ehttps://doi.org/10.3390/cancers17152469
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