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September 10, 2025Majalah Kesehatan IndonesiaOpen Access

The Effect of Nanocurcumin Administration on Plasma Malondialdehyde (MDA) Levels in Pregnant Wistar Rats (Rattus norvegicus) as a Preeclampsia Model

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Authors

SSSubandi SubandiLSLenny SariNNNurdiana Nurdiana

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Overview

Animal study finds nanocurcumin effectively lowers MDA levels in pregnant rats, suggesting antioxidant potential.

Key Points

  • Nanocurcumin administration significantly reduced malondialdehyde levels in preeclampsia models.
  • Rats receiving 25 mg/KgBW and 50 mg/KgBW of nanocurcumin had lower MDA levels compared to untreated groups.
  • Preeclampsia was induced using L-NAME, with plasma MDA measured via the Thiobarbituric Acid assay.
  • Findings highlight the potential of nanocurcumin as a therapeutic antioxidant in managing oxidative stress.

Cite This Study

Subandi et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479b503https://doi.org/10.47679/makein.2025226
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