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September 10, 2025OncoTargets and TherapyOpen Access

Advances in ORMDL Research in Malignant Tumors: A Review

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Authors

HWH. H. WangZYZhongQuan YiYSYang Song

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Overview

This review explores ORMDL proteins' influence on sphingolipid metabolism and tumor behavior.

Key Points

  • ORMDL proteins regulate sphingolipid metabolism, affecting cell growth and stress responses.
  • Research shows altered ORMDL expression in tumors like breast cancer and colorectal cancer.
  • Targeting ORMDL may provide promising strategies for cancer therapy and treatment.
  • Exploring ORMDL's role in the tumor microenvironment could enhance personalized medicine.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479ae31https://doi.org/10.2147/ott.s537194
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