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September 10, 2025Journal of CancerOpen Access

The Prediction Model for Triple-Negative Breast Cancer Prognosis and Immunotherapy Efficacy Based on Single-Cell Sequencing of CD8+ T cells

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Authors

JYJiarong YiYQYejun QiaoZXZhengchong Xiong

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Overview

Observed differences in prognosis and immunotherapy response in high- and low-risk TNBC patients, indicating potential for improved treatment strategies.

Key Points

  • Patients classified into high- and low-risk groups show significant differences in prognosis.
  • Single-cell sequencing identified 191 differentially expressed genes, aiding in prognosis prediction.
  • A regression model enabled risk grouping, correlating high-risk with poor prognosis.
  • Low-risk patients displayed better response to immunotherapy, suggesting tailored treatment approaches.

Cite This Study

Yi et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d6479aad6https://doi.org/10.7150/jca.115507
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