Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Journal of CancerOpen Access

Integrating Single-Cell and Bulk RNA Sequencing Reveals the Malignant Phenotype of CBX4 in Prostate Cancer

View Full Paper
Ask AI
Bookmark
Share

Authors

ZLZi-Hao LiuYLYang LiuZFZhiqiang Fu

Discussion

Loading...

Member takes

Overview

Observational analysis reveals high cbx4 expression correlates with advanced prostate cancer, suggesting its role in tumor progression.

Key Points

  • CBX4 was significantly up-regulated in prostate cancer tissues and cells, indicating its potential as an oncogene.
  • High expression of CBX4 is associated with advanced stage and poor prognosis of prostate cancer patients.
  • In vitro experiments showed that down-regulation of CBX4 inhibited cancer cell proliferation, invasion, and migration.
  • The study explores mechanisms by which CBX4 influences tumor immunosuppressive environment via signaling pathways.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d6479aacehttps://doi.org/10.7150/jca.115613
View Full Paper
Ask AI
Bookmark
Share