Procalcitonin Versus C-Reactive Protein: A Comparative Study for the Diagnosis of Neonatal Sepsis

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Discussion

Cross-sectional study compares procalcitonin and C-reactive protein in diagnosing neonatal sepsis, suggesting PCT is more accurate.

Procalcitonin shows higher diagnostic accuracy for neonatal sepsis compared to C-reactive protein.
PCT's sensitivity and specificity were found to be 74.3% and 43.4%, respectively, against blood culture.
This study involved 88 neonates suspected of sepsis, using data from blood cultures as the gold standard.
The findings advocate for the use of procalcitonin to enhance early detection and treatment strategies in neonates.

Shaukat et al. (2025) studied this question.

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