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September 10, 2025Endocrine ReviewsOpen Access

Innovative molecules and delivery technologies enabling the future of GLP-1-based therapies

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Authors

YXYining XuDDDaniel J. DruckerUniversity of TorontoGTGiovanni Traverso

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Implication

Review highlights challenges and opportunities for GLP-1-based agonists and drug delivery technologies.

Key Points

  • GLP-1-based therapies show promise in treating metabolic diseases, yet face challenges like high costs and injection needs.
  • Innovative delivery strategies, such as oral small-molecule agonists and implantable pumps, aim to enhance patient compliance.
  • Research on drug delivery technologies is vital for enhancing clinical outcomes and addressing limitations of current treatments.
  • Developing GLP-1 medicines requires consideration of endocrinological effects and patient-oriented needs to ensure success.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d64799ebchttps://doi.org/10.1210/endrev/bnaf027
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