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September 10, 2025Eastern Mediterranean Health JournalOpen Access

Comparative study of pap smear and polymerase chain reaction tests for human papillomavirus screening in Bahrain

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Authors

NSNermin Kamal SaeedSASafa AlshaikhMAMohammed Al‐Beltagi

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Overview

This study compares the diagnostic accuracy of pap smears and PCR for HPV detection, showing enhanced sensitivity. It highlights the importance of tailored screening programs.

Key Points

  • PCR testing showed higher sensitivity at 95.5% compared to the pap smear, indicating better detection of cervical abnormalities.
  • Among 320 samples, 56 were HPV-positive, leading to a positive predictive value of 94.6% for detecting lesions.
  • The study utilized chi-square and Fisher's exact tests for statistical analysis, ensuring robust comparisons between the two methods.
  • Combining HPV PCR with pap smear testing may enhance cervical cancer detection, suggesting a need for tailored screening programs.

Cite This Study

Saeed et al. (2025) studied this question.

synapsesocial.com/papers/68c24009b210217d64798ffehttps://doi.org/10.26719/2025.31.7.453
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cervical cytology diagnostic screening findings in pap smears: Insights from a Saudi tertiary center2025
  2. 2A Cross-sectional Study of Molecular Identification of Human Papillomavirus in Healthy Women With Normal Cytology in Ahvaz, Iran2025
  3. 3Cervical cancer risk and high-risk HPV types distribution in Saudi Arabia: Trends from a national laboratory-based study2025 · 4 citations
  4. 4Comparison of Self-Collected Versus Clinician-Collected Human Papillomavirus (HPV) Sampling for Cervical Cancer Screening: A Pilot Study in the United Arab Emirates2025
  5. 5Prevalence and Cytological Patterns of Cervical Lesions in Libyan Women: A Five-Year Pap Smear Analysis2025