Chemical and toxicological research on extracts from the leaves of Pittosporum senacia Poir. (Pittosporaceae), a medicinal plant endemic to Madagascar

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Chemical research shows toxic activity in extracts from Pittosporum senacia leaves, indicating potential risks.

E3 caused tissue lesions and central nervous system symptoms in mice at a lethal dose of 37.5 mg/kg.
The estimated LD50 for E3 was between 26.05 and 27.41 mg/kg, indicating significant toxicity.
In vitro tests showed that E3 had a minimum inhibitory concentration of 5.9 mg/ml against Staphylococcus aureus.
A phytochemical screening of E3 revealed phenolic compounds, unsaturated sterols, and triterpenes.

Vahinalahaja et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark