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September 10, 2025GSC Advanced Research and Reviews

In vitro antiplasmodial activity and phytochemical screening of crude extracts of Senna sieberiana DC. (Fabaceae), plant used in traditional medicine

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Authors

YSYoussouf SyllaUniversité Nangui AbrogouaJKJeanne Akissi KOFFIInstitut National de Santé PubliqueOYOumar Sounta YEOCentre National de Recherche Agronomique

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Implication

This study reports antiplasmodial activity of Senna sieberiana extracts, suggesting potential use as a traditional remedy.

Key Points

  • The methanolic extract of Senna sieberiana exhibited strong antiplasmodial activity with an IC50 of ≤ 5 µg/mL.
  • Testing included clinical isolates and reference strains NF54 and K1 of Plasmodium falciparum.
  • Different extraction methods were evaluated, highlighting the effectiveness of the methanolic extract.
  • Phytochemical analysis revealed the presence of polyterpenes, sterols, and flavonoids in the leaf extracts.

Cite This Study

Sylla et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d647982d3https://doi.org/10.30574/gscarr.2025.24.1.0215
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