Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025International Journal of Molecular SciencesOpen Access

TGF-β Signaling in Cancer: Mechanisms of Progression and Therapeutic Targets

View Full Paper
Ask AI
Bookmark
Share

Authors

ECElżbieta Cecerska‐HeryćAJAdrianna JerzykMGMałgorzata Goszka

Discussion

Loading...

Member takes

Overview

Analysis reveals TGF-β drives cancer progression through pathways like EMT, suggesting potential therapeutic targets.

Key Points

  • Disrupting tgf-β signaling contributes to cancer development and progression, indicating a key therapeutic area.
  • TGF-β initially inhibits the cell cycle but may later promote tumor growth and metastasis, highlighting its dual role.
  • Targeting tgf-β with pharmacological agents has emerged as a promising therapeutic strategy, improving treatment effectiveness.
  • Understanding the mechanisms of tgf-β signaling is crucial for enhancing survival rates in cancer patients; ongoing research is vital.

Cite This Study

Cecerska‐Heryć et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d64798264https://doi.org/10.3390/ijms26157326
View Full Paper
Ask AI
Bookmark
Share